Overview: generalized eruptive histiocytosis (General Eruptive Histiocytosis, GEH) as a papular, non-lipid nature, self-healing histiocytosis, occurs mainly in adults. 1963 by Winkelmann and Muller first reported a case of adults; 1987 Paputo other previously reported series of children's cases. The disease is extremely rare, reported in the literature about 30 cases, of which 7 were children.
pathogenesis is unclear. The clinical manifestations of disease and pathology as benign head with histiocytosis, disseminated xanthoma and xanthogranuloma overlap. Thus closely related.
generalized eruptive histiocytosis of early symptoms?
can occur at any age, asymptomatic lesions of the round or oval papules or nodules form, yellow or dark blue, solid nature, size 3 ~ 10mm . Successive groups of lesions, the number can be up to several hundred. Adult lesions, symmetrically distributed on the trunk and limbs, even to violate mucosa. Children's skin lesions irregularly distributed in the body, mucous membranes are not violated. Not involving the internal organs of adults and children. Skin lesions for several years, may gradually subside.
generalized eruptive histiocytosis ate?
generalized eruptive histiocytosis should be how to prevent?
currently no related content description.
generalized exanthematous histiocytosis precautions before treatment?
is self-limiting disease, without treatment.
(b) the prognosis
lesions for several years, may gradually subside.
generalized eruptive histiocytosis Chinese medicine treatment methods
No correlation Information
generalized eruptive histiocytosis Western treatment
generalized eruptive histiocytosis which checks should be done?
Histopathology: dermal papilla and dermal layer of the middle shows monomorphic cells and few lymphocytes. No multinucleated giant cells. Sparse nuclear chromatin organization, abundant cytoplasm, lightly stained, ill-defined cytoplasm. These cells often arranged in nests around the blood vessels. Immunohistochemical examination of infiltrating cells in S-100 protein and CD1a (OKT-6) negative, CD-11b and CD-4 positive. AMD examination showed clusters of tumor cells containing large amounts of dense lamellar body rules, even visible insect-like body, no Birbeck granules. Tissue lipid stain was negative.