Overview: changed proteus (proteus bacillus) are opportunistic pathogens, causing food poisoning due to intake of contaminated food due to Proteus. The main clinical manifestations of gastrointestinal type and allergic-type, the former more common.[Cause]
proteus enterobacteriaceae Gram-negative bacilli, were pleomorphic, There are whole body flagella, no spores, no capsules, sports and lively. Facultative anaerobic, nutrition, less demanding, in nutrient agar and blood agar can grow, optimum growth temperature 10 ~ 43 ℃, the colonies were often characterized by crawling, do not form a single colony, such as the amount of increase to 5% agar, obtain single colonies. In the blood agar plate with hemolysis. Biochemical characteristics of hydrogen sulfide-positive, positive for phenylalanine deaminase, urease strongly positive. antigenic structure of bacteria (O) and flagellar (H) two. according to different antigenic and biochemical properties, the proteus divided into: general proteus (P.vulgaris), P. mirabilis (P.mirabilis), 产 adhesion of proteus (P.myxofaciens) and Pan's proteus (P.penneri .) Were mainly caused by food poisoning for the first three.
(B) the pathogenesis
and whether or not the disease severity and the number of bacteria ingested (generally considered up to 105 / g or more), and the toxins produced by the body defenses and other factors. proteus virulence is mainly produced by intestinal bacteria toxins. proteus can be combined to produce a cell hemolysis factor (cell-bound hemolytic factor), on human transitional cell has good adhesion and strong invasion force. Some strains can produce α hemolysin, cytotoxic effects. proteus can also produce histidine decarboxylase, meat can become a histamine histidine decarboxylase, histamine caused a similar intake of more than 100mg of histamine poisoning allergies.[Sign]
suspicious, according to food consumption, total food by the collective performance of the incidence and clinical preliminary diagnosis can be made. proteus in the food poisoning bacteria may be due to the different type, quantity, different metabolites, and different symptoms. Common type with gastroenteritis and allergic-type, or the same patient both.
1. gastroenteritis-type incubation period 3 ~ 20h, rapid onset, nausea, vomiting, abdominal pain, diarrhea, watery diarrhea, with mucus, odor, no pus, several times a day to a dozen. 1 / 3 to 1 / 2 in patients with gastrointestinal symptoms, fever with chills, lasted several hours and then decreased. In severe cases, dehydration or shock.
as proteus parasites in the normal intestine, the food can be contaminated by Proteus. Therefore, any suspected proteus poisoning should take suspicious food, vomit and feces for bacterial culture, separable from the same type of Proteus. Isolated Proteus, hemagglutination test must be made to confirm. proteus vulgaris on OX19, proteus mirabilis, the agglutination titer of OXK should be increased by more than 4 times, be certain diagnosis. Such as indirect hemagglutination test, the sensitivity can be increased 2 to 16 times. In recent years, proteus application of urea (urea), phenylalanine (phenylalanine), hydrogen sulfide (hydrogen sulfide) established a quick biochemical characteristics of simultaneous qualitative and quantitative detection methods-UPS method. Correct identification rate of 100%, sensitivity is the spread of the growth of the past 100 times observation, reporting time from the previous 4 to 15 days decreased to 4 ~ 24h. And high precision, specificity, not subjects like species and other factors.[Aftertreat]
should buy sterilized milk without buying raw milk, fruits, vegetables must be washed clean; thorough heating of food, all parts of the food must reach a temperature above 70 ℃; cooked food storage time should not be too long, it is best eaten as soon as possible after the pan in the food; proper storage of cooked food should be above 60 ℃ or 10 ℃ storage of cooked food under the following conditions; storage of cooked food thoroughly before consumption must again heating, the heating temperature should reach all parts of the above 70 ℃; avoid contact with cooked food and raw food, for handling raw and cooked food, knives, chopping board to be separated to avoid cross-infection; attention to hand washing before food preparation and processing intermittent production must again washed hands; maintaining clean utensils and kitchen, all the utensils used for provisioning the surface of the food must be kept absolutely clean cloth should be changed every day, and boiled before use in the next disinfection; prevent insects, rodents and other animal contact with food; drink safe water, do not drink unboiled water[Prevent]
food contamination rate from 3.8% to 100%, with fish, crabs and meat contamination is higher. food infection correlated with the freshness of food, transportation health are closely related. Higher prevalence in summer and autumn, in recent years, the incidence of this disease on a downward trend.[Treat]
1. damp gastrointestinal: nausea, vomiting, abdominal swelling, abdominal pain, diarrhea, urgency, or diarrhea and unhappy, and fecal color yellowish and smelly, anal burning, fanre thirst, short yellow urine, red tongue yellow greasy moss, pulse number or slip number. heat and dampness. Vector according to silkworm burning soup or decoction.
2. enteric alpine card: diarrhea thin, and even water-like, abdominal pain, bowel, abdominal nausea eat less, and have chills or fever, greasy tongue coating , pulse slow. cold dehumidification. Huo Xiang Zheng qi Decoction, Weiling Tonga or rugosa, wood and other.
3. stagnation gastrointestinal symptoms: vomiting, acid sour, poor appetite, anorexia, abdominal pain, diarrhea, vector gas rancid, bowel, pain reduction after diarrhea, fecal odor, such as lost eggs, nausea, vomiting, abdominal distention, dirt cloud or thick fur greasy, digestion dredge. Paul and pill zhishi Daozhi Pill.
4. jin qi deficiency syndrome: vomiting on the collapse, thirst lead to drink, Shenpi shortness of breath, dry skin, sunken eyes, red Taigan, weak pulse breakdown . qi Sheng Jin. shengmaisan add yams, Dendrobium, ebony, white peony root and so on.
5. sun off the card: loose stool, can not help but slip, nausea, vomiting, pale limbs Jueleng, cold sweat dripping, trance, pale tongue, smooth, pulse micro-or floating rootless. Back to the sun solid off. Hui yang emergency decoction.
unilateral prescription: (1) purslane 30g, sophora flavescens 15g, decoction. (2) hawthorn 120g, magnolia 10g, decoction. (3) CSC 15g, houttuynia 15g, treats 6g, decoction. (4) The amount of fresh garlic, fresh clothes. (5) fern 30 to 60 grams, decoction.
drug treatment: 1. gastroenteritis-type
② antimicrobial treatment: norfloxacin may use for severe 0.2g / time, 4 times / d, or chloramphenicol 0.25 ~ 0.5g / time, 4 times / d, orally.
4. vomiting, severe, treatment may be given anti-emetics, such as chlorpromazine, atropine, metoclopramide, metoclopramide, etc.
8. be taken to avoid shock, heart failure and other serious complications.[Examine]
obtained acute and convalescent patients (poisoning, 12 ~ 15d) of the serum, made with isolates determination of serum agglutination titer, titers higher than the acute phase of recovery titer four times, that have diagnostic significance. In both healthy people as controls, should be negative.
take suspicious food, vomit and feces for bacterial culture, separable from the same type of Proteus. Isolated Proteus, hemagglutination test must be made to confirm. proteus vulgaris on OX19, proteus mirabilis, the agglutination titer of OXK should be increased by more than 4 times, be certain diagnosis. Such as indirect hemagglutination test, the sensitivity can be increased 2 to 16 times. In recent years, proteus application of urea (urea), phenylalanine (phenylalanine), hydrogen sulfide (hydrogen sulfide) established a quick biochemical characteristics of simultaneous qualitative and quantitative detection methods-UPS method. Correct identification rate of 100%.[Diff]
suspicious, according to food consumption, total food by the collective performance of the incidence and clinical preliminary diagnosis can be made. stool culture was proteus can be seized. Agglutinating antibodies in the diagnosis. This disease and cholera and cholera, acute bacillary dysentery, viral gastroenteritis, food poisoning and other non-bacterial diseases.[Disease]
premature loss of masticatory function-related diseases
more dental symptoms
after tooth extraction wound prolonged bleeding after tooth extraction without teeth during the day or unconsciously, will lead tusk gum bleeding gums line of gingival hyperplasia gingivitis chewing gum swelling of premature loss of functional jaw was "fan" sudden jaw bone deformity green or brown teeth incisor teeth buried tooth spacing widened eruption delay missing molar teeth, wisdom teeth alveolar type yellow light gray
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